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Luxury Longevity & Medical Wellness Retreats

Five-Star Wellness Resorts, Medical Spas, and Longevity Clinics Worth Booking.

The best destination luxury longevity clinics and medical wellness retreats combine world-class hospitality with cutting-edge health programs, offering a more considered alternative to traditional spa resorts or lifestyle wellness hotels. 

This curated selection of renowned wellness hotels brings together luxury wellness resorts, medical spas, and longevity clinics that meet Jetset Select standards, spanning established European medical destinations, discreet Asian wellness sanctuaries, and select North American properties known for quality and care. 

Each property was selected for its level of medical or wellness depth, overall luxury experience, and ability to deliver a high-trust stay where expertise, discretion, and long-term well-being take precedence over trends, ensuring every recommendation reflects both serious health intent and five-star standards.

Featured Luxury Longevity & Medical Wellness Resorts

Choose a property to view details and availability.

Clinique La Prairie | Best Luxury Wellness Retreats | Luxury retreats | wellness hotels | wellness retreats | longevity retreats | St Regis Bangkok | Clinique La Prairie Bangkok
Clinique La Prairie
SHA Wellness Clinic in Spain, a luxury wellness resort on the Mediterranean with sleek modern architecture and terraces overlooking the sea, known for the SHA Method, high-end wellness for aging, and transformative wellness retreat Spain programs.
SHA Wellness Clinic
Grand Resort Bad Ragaz in Switzerland, a luxury wellness and longevity retreat with sleek medical spa facilities and mountain views, offering advanced anti-aging treatments, regenerative medicine, and personalized health optimization programs.
Grand Resort Bad Ragaz
Palazzo Fiuggi luxury wellness hotel in Fiuggi Terme, Italy, a hillside medical spa resort with grand historic architecture, outdoor terraces, and views over the countryside, known for luxury longevity, detox, and holistic wellness programs
Palazzo Fiuggi
Beachfront view of Chiva-Som in Hua Hin, Thailand, a serene luxury wellness retreat with tropical gardens, open-air pavilions, and a renowned luxury spa offering personalized programs at one of Thailand’s best luxury wellness hotels.
Chiva-Som Resort
Sensei Lānaʻi, A Four Seasons Resort is a discreet luxury wellness resort and luxury yoga retreat in Hawaii, offering science-led wellness programs, personalized health consultations, spa therapies, and mindful movement in a private, adults-focused setting on the island of Lānaʻi. Developed in partnership with Sensei, the resort is widely regarded as one of the best luxury wellness retreats in Hawaii for travelers seeking structured health optimization, longevity-focused wellness travel, and refined Four Seasons hospitality.
Sensei Lanai, a Four Seasons Resort
Zulal Wellness Resort Zulal Qatar Best Luxury Wellness Resorts Best Luxury Wellness Retreats Jetset Select
Zulal Wellness Resort
Hacienda AltaGracia is a luxury wellness resort in Costa Rica, offering immersive nature-led wellness programs, spa and healing therapies, and holistic health experiences set within a private rainforest reserve. Known for its integrative wellness approach, elevated design, and destination-level serenity, it ranks among the best luxury wellness retreats in Costa Rica for restorative wellness travel and refined eco-luxury stays.
The Well at Hacienda AltaGracia
Six Senses Vana in India is a Six Senses destination spa and luxury wellness resort that blends ancient healing traditions with high-end wellness programs and modern integrative therapies. Positioned among the best luxury wellness retreats and spa resorts in Asia, this Six Senses resort operates as a luxury longevity retreat with structured wellness retreats focused on detox, stress relief, weight loss, and deep rest. Guests choose Six Senses Vana for immersive, all-inclusive-style wellness experiences comparable to leading global names such as Miraval Resort, The Retreat Costa Rica, and Pritikin Longevity Center, making it a benchmark for luxury spa resorts, biohacking retreat-style offerings, and transformative luxury retreats.
Six Senses Vana
Terme di Saturnia Thermal Spa Wellness Resort Best Luxury Wellness Resorts Best Luxury Wellness Retreats Luxury Longevity Clinic Jetset Select
Terme di Saturnia Hotel & Thermal Resort
The Bürgenstock Hotel & Alpine Spa is one of Europe's top luxury wellness hotels in lucerne and a top-rated lake lucerne switzerland hotel, blending historic glamour with modern design and offering breathtaking lake views. direct access to a vast Alpine Spa with panoramic pools, and multiple acclaimed restaurants, making Burgenstock one the world's top luxury wellness hotels and resorts.
Bürgenstock Hotel & Alpine Spa
Kamalaya Koh Samui wellness sanctuary overlooking the Gulf of Thailand, featuring hillside villas, spa facilities, and jungle surroundings at Kamalaya Resort, a luxury resort in Thailand and renowned Kamalaya wellness sanctuary and holistic spa resort in Koh Samui, Thailand, ideal for Thailand luxury trips and travelers seeking luxury hotels in Thailand and refined Thailand beach resorts.
Kamalaya Koh Samui

Each destination guide is updated regularly to reflect availability, new openings, and quality standards.

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